The Buffalo Bills lost rookie quarterback Josh Allen to an elbow injury in the third quarter, then saw his backup throw a game losing interception with just 90 seconds remaining. In the end, the Bills squandered a great defensive performance in a 20-13 defeat on the road to the Houston Texans. And, as of Sunday night, the severity of Allen's injury was unclear, but he did not return.

Nathan Peterman came on in the third quarter after Allen left. Immediately following a recovered fumble by the defense, he led the Bills to a go ahead touchdown early in the fourth - connecting for a 16-yard score to Zay Jones to give Buffalo a 13-10 advantage.

With the game tied 13-13 and under two minutes to play in regulation, Peterman was intercepted - a pick that was returned 28-yards for the game winning score. Peterman was also intercepted on the ensuing possession.

The Bills' defense sacked Houston's Deshaun Watson seven times and forced three turnovers - a pair of picks and a fumble. They held the Texans to 219-yards of total offense.

Buffalo totaled 229-yards.

Allen was 10-of-17 for 84-yards, no TDs, no INTs. Peterman finished 6-of-12 for 61-yards a touchdown and the two picks. LeSean McCoy ran for 73.