New York, NY (WIBX) - Nora Ephron, the screenwriter and director behind the hit movie "When Harry Met Sally" has died from pneumonia brought on by acute myeloid leukemia. She was 71.

Ephron began her career in the 60s as a journalist for the New York Post, but also wrote essays for Esquire and other publications. She also wrote the novel 'Heartburn' in 1983, based loosely on her failed marriage to Carl Bernstein.

But, she is best known for her work with actors such as Tom Hanks and Meg Ryan, who starred in 1993's "Sleepless in Seattle" and "You've Got Mail" in 1998.

She also directed "Julie and Julia" in 2009, writing the screenplay adaptation of the book.

Ephron leaves behind her husband Nicholas Pileggi and her sons Jacob and Max Bernstein.