The Indianapolis Colts scored a satisfying upset victory over their former franchise centerpiece Peyton Manning on Sunday night, but it appears they will now be without a receiver who has been an offensive staple for the last decade - Reggie Wayne - who is likely lost for the season. 

ESPN.com is reporting that Wayne - who helped the team flourish during Manning's tenure in Indy - suffered a torn ACL in the team's 39-33 win over the Broncos in Week 7.

The injury came on a play where Wayne was not hit hard, or rolled-up on, but rather when he tried to suddenly put on the brakes to adjust to a pass from quarterback Andrew Luck. Wayne collapsed in pain, and while he did walk to the locker room on his own power, he was limping noticeably, and crying.

Wayne was leading the team in receptions and receiving yards this season - 38 for 503 yards and 2 TD's - and was the franchise's leading receiver in seven of the previous nine seasons.

The Colts (5-2), who currently lead the AFC South division, will try to fill Wayne's big shoes with WR's T.Y. Hilton, Darrius Heyward-Bey and Coby Fleener.

Indianapolis Colts 2013 statistics